Agilent/Keysight U2354A

The Keysight U2354A is a multifunction USB data acquisition module delivering 16-bit analog input and programmable digital I/O in a compact form factor. This DAQ device acquires analog signals at up to 500 kSa/s across 16 single-ended or 8 differential channels, with 24-bit digital I/O and dual counter channels for timing and event measurement. Operating as a standalone instrument or integrated into a U2781A USB modular chassis, the U2354A supports design validation, manufacturing test, data logging, and physical measurements across engineering and research applications.

Technical Specifications

• Analog input: 16 single-ended or 8 differential channels, 16-bit resolution


• Sampling rate: Up to 500 kSa/s


• Input voltage range: 0 to 12 V


• Maximum input current: 10 µA


• Analog bandwidth: 400 kHz


• Digital I/O: 24-bit programmable TTL channels


• Counter channels: 2 general purpose


• Onboard memory: 8M points


• Interface: Hi-Speed USB 2.0 (USBTMC-USB488)


• Dimensions: 182.4 mm × 120 mm × 44 mm


• Weight: 565 g


• Operating temperature: 0°C to +55°C

Key Features

• Configurable as digital multimeter (polling mode) or oscilloscope (continuous mode with triggering)


• Burst mode for simulated simultaneous analog acquisition


• Self-calibration to maintain offset accuracy


• Standalone or modular chassis operation


• Includes BenchVue software license and Keysight Measurement Manager (AMM)


• Optional terminal blocks (U2901A, U2902A) for field connections

Typical Applications

• Design validation and prototyping


• Manufacturing test and process monitoring


• Data logging and sensor interface


• Physical measurements and environmental monitoring

Compatibility & Integration Operates under Microsoft Windows with support for Keysight VEE, MATLAB R2007a, NI LabVIEW, Microsoft Visual Studio, and C++/C#/VB development environments. Integrates with U2781A USB modular instrument chassis for expanded measurement systems. Product discontinued June 1, 2024; Keysight provides five-year post-discontinuation support.